In embryonic stem (ES) cells, bivalent chromatin domains with overlapping repressive (H3 lysine 27 tri-methylation) and activating (H3 lysine 4 tri-methylation) histone modifications mark the promoters of more than 2,000 genes.To gain insight into the structure and function of bivalent domains, we mapped key histone modifications and subunits of Po
Background: Medical negligence is an increasing public health concern among healthcare providers worldwide as it affects patient safety.It poses a significant risk of patient injury, disease, disability, or death.The WHO has recognized deficiencies in patient safety as a global healthcare issue to be addressed.This study aimed to analyze various co
Questions of the quality of computer-based models and the formal processes of model testing, involving internal verification and external validation, are usually given only passing attention in engineering reports and in technical publications.However, such models frequently provide a basis for analysis methods, Collections design calculations or r
The absence of a unified material legal regulation of the transfer of property rights is determined by the presence of fundamental contradictions in the approaches of various legal systems to this issue.The lex rei sitae connecting factor is not the optimal way to regulate the transfer of ownership of movable property in cross-border transactions.C